"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

Required Reading
Activism and Advocacy
Calorie Restriction
The Community, Visualized
Cryonics
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
Methuselah Foundation
Mprize for Anti-Aging Research
Stem Cells, Regenerative Medicine
SENS, Negligible Senescence
What is Anti-Aging?

High Quality Supplements, Vitamins
High Quality Supplements, Vitamins

On the Causes of Aging
Accumulating AGEs
Aging Immune System
Junk in the Lysosome
Mitochondrial Free Radicals
Other Causes of Aging

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
The Tithonus Error
What About Retirement?

Recent Entries

  • On the Erosion of Telomeres
  • Things We Don't Need To Know In Order To Cure Aging
  • The Value of a Longevity Therapy
  • On Expanding the Audience
  • Timelines For Agelessness Through Medical Technology
  • Understanding Aging Conference, Los Angeles, June 27th
  • Upgrading Mitochondrial DNA to Cause Less Damage
  • Our Bioartificial Future
  • What is Cryonics?
  • Electric Pulse Interview With Aubrey de Grey
  • "Should" is a Dangerous Word
  • Small Steps Towards Engineered, Hyperefficient, Artificial Immune Systems
  • An Interview With Peter Thiel
  • The Latest Rejuvenation Research, April 2008
  • Comments on the Sirtris Acquisition
  • Body Temperature and Longevity
  • A Look at the Longevity Dividend View
  • Thrashing Out Your Regenerative Medicine Thesis Online
  • But Enough About You
  • Aging Doesn't Just Kill People, It Kills Them Horribly

    Weblogs of Interest
    Accelerating Future
    Ageing Research
    Alcor News
    April's CR Diary
    Andart
    Anti-Aging Medicine & Science
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Digital Crusader
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Frontier Channel
    Future Current
    FuturePundit
    grailsearch.org
    Longevity Science
    Marginal Revolution
    Metamagician and the Hellfire Club
    Methuselah Foundation Blog
    Mises Economics Blog
    Nanodot
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
    Responsible Nanotechnology
    ScienceBlogs
    Sentient Developments
    Singularity Institute Blog
    The Loom
    The Speculist
    Tangled Bank
    Transumanar

      
    Search

    Archives (Monthly)

    May 2008
    April 2008
    March 2008
    February 2008
    January 2008
    December 2007
    November 2007
    October 2007
    September 2007
    August 2007
    July 2007
    June 2007
    May 2007
    April 2007
    March 2007
    February 2007
    January 2007
    December 2006
    November 2006
    October 2006
    September 2006
    August 2006
    July 2006
    June 2006
    May 2006
    April 2006
    March 2006
    February 2006
    January 2006
    December 2005
    November 2005
    October 2005
    September 2005
    August 2005
    July 2005
    June 2005
    May 2005
    April 2005
    March 2005
    February 2005
    January 2005
    December 2004
    November 2004
    October 2004
    September 2004
    August 2004
    July 2004
    June 2004
    May 2004
    April 2004
    March 2004
    February 2004
    January 2004

    Creative Commons License
    Attribution, noncommercial, no derivative works. Play nice.

  • « The Oldest Dies, As The Oldest Has Again and Again | Main | To What Degree Is a Robust Cancer Cure Sufficient? »

    Saturday, January 20, 2007

    Why Vitrify the Body?

    If you are one of the hundreds of millions unfortunate enough to face death by aging prior to the advent of medical technologies capable of rejuvation - of reversing aging by repairing age-related cellular damage - there is still one option remaining to give you a chance at renewed life in the future. This option is cryopreservation: paying a service provider such as Alcor to vitrify your body immediately following clinical death for indefinite low-temperature storage.

    Cryonics is the only option for life extension open to many older and seriously ill people: those who cannot wait for the promised therapies of the next few decades. It is the science of placing humans and animals into a low-temperature, biologically unchanging state immediately after clinical death, with the expectation that advances in medical technology may eventually enable full restoration to life and health. A small industry of cryonics providers exists to freeze or vitrify your body on death, in the hopes that future scientists (most likely using nanotechnology and nanomedicine) will be able to revive and repair you.

    The practice of cryonics is an ongoing medical experiment with an unknown chance of success. Responsible cryonicists understand that cryonic suspension is an educated gamble. The chances are certainly better than zero, however, and as one wag noted, "the control group in this experiment isn't doing so well." By this, he was referring to the vast number of people who are cremated, buried or otherwise interred. The chances of any plausible future science restoring them is zero. Cryonic suspension is, after all, only the second worst thing that can happen to you.

    You are your brain. More precisely, you are a particular arrangement of molecules and fine structures in your brain - structures that are undamaged at small scales by appropriately managed vitrification or freezing. Hurdles remain, however, both in terms of preventing comparatively large-scale fractures, and suitable preparations to reduce cell damage after clinical death but prior to processing for cryopreservation in all cases (including accident). The hurdle of restoring a cryopreserved, fracture-bearing individual to health and life is left to the scientists of the future: it's a challenge, but certainly not one made impossible by the laws of physics. Indeed, we can envisage the classes and capabilities of technology needed quite clearly today, if not the details.

    In principle we need only repair the frozen brain, for the brain is the most critical and important structure in the body. Faithfully repairing the liver (or any other secondary tissue) molecule by molecule (or perhaps atom by atom) appears to offer no benefit over simpler techniques -- such as replacement. The calculations and discussions that follow are therefore based on the size and composition of the brain. It should be clear that if repair of the brain is feasible, then the methods employed could (if we wished) be extended in the obvious way to the rest of the body.

    The brain, like all the familiar matter in the world around us, is made of atoms. It is the spatial arrangement of these atoms that distinguishes an arm from a leg, the head from the heart, and sickness from health. This view of the brain is the framework for our problem, and it is within this framework that we must work. Our problem, broadly stated, is that the atoms in a frozen brain are in the wrong places. We must put them back where they belong (with perhaps some minor additions and removals, as well as just rearrangements) if we expect to restore the natural functions of this most wonderful organ.

    Here's a question: if this level of advanced nanotechnology is required to repair your brain, isn't it fair to assume that building a new body to house your brain is a given at that level of progress? After all, we're not all that far away from being able to cultivate entire replacement organs from stem cells today. If you must undergo cryopreservation, because you were born too soon for the future of rejuvenation medicine, why bring your body along?

    The cost of cryopreservation for your head alone is half that of the whole body. Think for a moment: if the objective is to survive to see a future capable of reviving you some number of decades from now, what is more likely to help? Resources - your money - given to preserving your body below the neck, or those same resources dedicated to supporting, growing and otherwise firming up the organization, science and technology base that will be maintaining your storage all those years?

    It seems the rational choice to me to preserve your head - your brain - and give the difference to cryonics research and organizational support. Better to make the future revivers expend a little more effort than to fail to do your part to help your cryonics provider (a) carry through to that era and (b) expand their capacity to offer service to more people.

    Technorati tag:

    Posted by Reason at January 20, 2007 8:22 PM | TrackBack (1)

    Posted by: Infidel753 at January 21, 2007 8:08 AM

    Even if the vitrified brain cannot be restored to full normal functionality, another revival option might be uploading. Provided the synaptic patterns making up the individual's personality, memories, etc. are sufficiently well preserved, it would be theoretically possible to scan the entire brain at high resolution and run the same "programs" on a computer. (Right now we don't have such scanning ability or powerful-enough computers, but in a few decades we will.) The individual would then be alive and conscious again, and able to deal with the world either through virtual reality (where a great deal of human interaction will probably take place by then), or via a two-way neurological interface with a specially-grown physical body, or via other options we can't think of yet.

    "You" are not even your physical brain, but rather the set of "programs" wired into the synapses of your brain. Those are what must survive.

    [Posted by: Infidel753 at January 21, 2007 8:08 AM]

    Posted by: Jens Rabis at January 22, 2007 3:25 AM

    Our mothers make also nothing else: Babies from atoms and molecules assemble. The atoms and molecules come from the food and air. We will be able to copy that sometime also technically. An unpleasant feeling has I in the meantime because of the brain atomically scanning. Does not function, without destroying the brain. If it should function, I would be a copy, because the original “lives” still. It would be at present more pleasant me: Vitrification of the brain. Reon purchasing with artificial body in a few hundred years. Afterwards slow exchange of the biological one against inorganic “cells”. That would be “slow metabolism”. I would bear that psychologically better. Perhaps I do not have in few years more courage, but at present. And it? With best greeting Jens Rabis

    [Posted by: Jens Rabis at January 22, 2007 3:25 AM]

    Posted by: Jens Rabis at January 30, 2007 1:00 AM

    Appointment on the subject:

    Famous Cryonics meet from the 18th to the 20th May, 2007 in Florida (USA) to report about her latest results.

    Among the performers are among other things Gregory M. Fahy, Brian Wowk and Ben Best.

    The conference is organized by relatively young company Suspended Animation. In the conference pamphlet one says, one will demonstrate an extremely ambitious research plan. This has a reversible whole body-Vitrifikation to the purpose. As a big specific feature the reversal of this procedure should get by without nano technological cell repair. With accordingly big interest this research plan is expected from the professional world.

    Download Brochure: http: // www.suspendedinc.com / conference / SA_conference.pdf

    [Posted by: Jens Rabis at January 30, 2007 1:00 AM]

    Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising and other forms of inappropriate behavior are likely to be deleted.










    Remember personal info?