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  • « Write About Healthy Life Extension: a $20 Blogging Challenge | Main | Keeping an Eye on the Infrastructure Technologies »

    Friday, March 7, 2008

    On the Way to Writing Off Telomolecular

    Well, this is disappointing, to say the least:

    According to Senior Vice President, David Dollar, "This is a revolutionary face cream - a product so different and innovative, we believe it could generate enormous consumer interest."

    So much for that company, you know, the one that was promising really interesting things in telomere and mitochondrial science not so long ago:

    Telomolecular Corporation [recently] acquired a new technology from Stanford Leland Jr. University. The technology, called Mitofusin 1, allows for the repair of damaged mitochondrial DNA. Damage to mitochondrial DNA leads to forms of aging and a variety of diseases.

    What do we get out of the far end of the pipe? Another useless "anti-aging" potion manufacturer - as through we had a deficit of those, not enough salespeople clogging up public understanding of what is plausible in longevity research. While recognizing that we all thrive only by paying our respects at the temple of Mammon, it is disheartening to see yet another organization taking the path of least resistance and least promise. It is a shame, a tragedy, that the oppressive state of medical regulation in the developed world makes this an almost expected outcome. It is far, far easier to make a living unmolested in the provision of bread and circuses than to build something new and valuable with a boot pressed to your neck.

    Incentives matter - and the FDA refuses to approve anything that might actually repair some form of age-related damage. Any medical application that might actually be approved to treat an FDA-approved disease is forced through insanely expensive, unnecessary and overwrought trial processes - unless of course it is one of the many, many new medical technologies that is discarded as not cost-effective in the face of this huge barrier.

    So it is we have an ocean of "anti-aging" nonsense, bread and circuses with only the most tenuous connection to science of interest, because government regulators have made that the best road to a profit. Ultimately, venture investors will, as for most people, demand profits over the warm feeling of altruism and frustrations of trying to do good that unelected, unaccountable government employees have decided should not be done.

    The systems and organizations of medicine and medical research are nothing short of insane in their structure and actions; a sea of waste and walls to block those best placed and eager to turn dreams into reality. It is long overdue a revolution.

    Posted by Reason at March 7, 2008 8:44 PM | TrackBack (0)

    Posted by: ShrinkWrapped at March 8, 2008 7:11 AM

    I couldn't agree with you more about how foolish and self-defeating our regulatory environment is. What will change the calculus is the day an anti-AGE compound is approved for use in Diabetes. The following day there will be established an off-label market worth multiple billions. Think of anti-AGE Rx as a "proof of concept" for SENS. Venture capital floodgates will open.

    [Posted by: ShrinkWrapped at March 8, 2008 7:11 AM]

    Posted by: David Dollar at March 12, 2008 9:02 AM

    Don't be disappointed!!! Our core mission to develop cancer therapies and therapies for age related diseases has not changed. As you are aware, it is difficult to navigate the complexities of the FDA and SEC these days. We are using our technologies to produce novel new comsumer products that should sell very well. We plan to use these revenues to fund our research and fund the very expensive road through the FDA. We have made some good progress with our cancer therapies and telomere elongation therapies. Due to SEC concerns I can not comment in detail publicly, but I would estimate we will have some sort of public annoucment by the end of the year.

    Best regards,

    David Dollar
    Senior Vice President
    Telomolecular Corp.

    [Posted by: David Dollar at March 12, 2008 9:02 AM]

    Posted by: Ben at March 12, 2008 7:58 PM

    Thanks for posting David.

    We appreciate your efforts. It's important that businesses such as yours are allowed to go on being profitable in order to continue your research, and I think everybody understands that.

    Furthermore, I view the cosmetic treatment of aging as a pretty important first step. Why? Because it will have results people can see. Skin rejuvination is going to play a big part in creating public awareness of potentially succesful antiaging technoloigies as it will convinve the general ublic that this is possible. It's very important.

    And besides, looking young and healthy is a big part of being young and healthy - so why not?

    [Posted by: Ben at March 12, 2008 7:58 PM]

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