"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

Required Reading
Activism and Advocacy
Calorie Restriction
The Community, Visualized
Cryonics
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
Methuselah Foundation
Mprize for Longevity Research
Stem Cells, Regenerative Medicine
SENS, Negligible Senescence
What is Anti-Aging?

On the Causes of Aging
Accumulating AGEs
The Failing Immune System
Junk in the Lysosome
Mitochondrial Free Radicals
Senescent Cells
Other Causes of Aging

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
The Tithonus Error
What About Retirement?

Recent Entries

  • Reliably Taking Care of Your Health Matters in the Long Term
  • Reactive Oxygen Species and Stem Cell Decline
  • New SAGE Crossroads Podcasts on the Evolution of Aging
  • Antioxidants
  • Cancer in the Context of Immune System Aging
  • My Project 10100 Submission: Mitochondrial Repair
  • Google's Project 10100 Initiative
  • Ouroboros at the Cold Spring Harbor Labs Conference
  • An Overview of Longevity Genes
  • The Integrative Genomics of Aging Group
  • Also, Try Not To Stab Yourself Repeatedly
  • Glycation Versus Your Mitochondria
  • Iron in the Lysosome
  • Calorie Restriction Changes Your Biochemistry For the Better
  • The New New Advertising Policy
  • Ferociously Complex, Is Metabolism
  • Telomeres, Health, and Centenarians
  • I Will Wager That These Mice Live Longer Too
  • Perspective
  • Why Aren't You Exercising Already?

    Weblogs of Interest
    Accelerating Future
    Ageing Research
    Anti-Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Frontier Channel
    Future Current
    FuturePundit
    grailsearch.org
    Longevity Science
    Marginal Revolution
    Metamagician and the Hellfire Club
    Methuselah Foundation Blog
    Mises Economics Blog
    Nanodot
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
    Responsible Nanotechnology
    ScienceBlogs
    Sentient Developments
    Singularity Institute Blog
    The Loom
    The Speculist
    Tangled Bank
    Transumanar

      
    Search

    Archives (Monthly)

    October 2008
    September 2008
    August 2008
    July 2008
    June 2008
    May 2008
    April 2008
    March 2008
    February 2008
    January 2008
    December 2007
    November 2007
    October 2007
    September 2007
    August 2007
    July 2007
    June 2007
    May 2007
    April 2007
    March 2007
    February 2007
    January 2007
    December 2006
    November 2006
    October 2006
    September 2006
    August 2006
    July 2006
    June 2006
    May 2006
    April 2006
    March 2006
    February 2006
    January 2006
    December 2005
    November 2005
    October 2005
    September 2005
    August 2005
    July 2005
    June 2005
    May 2005
    April 2005
    March 2005
    February 2005
    January 2005
    December 2004
    November 2004
    October 2004
    September 2004
    August 2004
    July 2004
    June 2004
    May 2004
    April 2004
    March 2004
    February 2004
    January 2004

    Creative Commons License
    Attribution, noncommercial, no derivative works. Play nice.

  • « Thrashing Out Your Regenerative Medicine Thesis Online | Main | Body Temperature and Longevity »

    Wednesday, April 23, 2008

    A Look at the Longevity Dividend View

    As I mentioned over at the Longevity Meme, SAGE Crossroads seems to be putting forth new material on policy and longevity science once more. Looking at some of the podcasts uploaded this year, I notice one on the Longevity Dividend initiative with Daniel Perry of political advocacy groups Alliance for Aging Research and CAMR, amongst others.

    #35-Longevity Science-Setting the stage, the longevity dividend:

    All you have to do is go into any bookstore in this country and go to the health section and you’ll see lots of titles about ending aging or immortality or stopping aging in its tracks. I think there is a lot of debate over whether that’s conceivable, but I think there is an emerging belief that we can slow down the processes of aging and make real achievements within a reasonable period of time, the next 10-15 years, that could buy back for people now living 5-7 years of healthy, productive life. As one gerontologist said, it ought to take 80 years to get to 60. Now that may be a bit more ambitious that what I’m talking about. I’m talking about seven years not 20 years, but there is a growing feeling among leading scientific authorities that based upon what we know works in laboratory animals, including apparently based on recent data, rhesus monkeys, a very close cousin to human beings. It could be possible that we could engineer healthier, more vital, more satisfying life for people in their 70s, 80s, and 90s in our lifetime.

    Institutional outlooks are usually incrementalist, aiming for the smallest set of changes possible under present circumstances, as the incentives within institutions discourage any other course. In that respect, the Longevity Dividend is the output of institutional thinkers. What you see above this is more or less the view from inside the government funding monolith, where suggesting even a modest target for increasing healthy life span is a major advance, hurdle and negotiation.

    Meanwhile, outside the institutional gates is where you'll find the serious attempts to create revolutionary change in the aging research community and develop disruptive technologies from the latest longevity science. As I said at the time the Longevity Dividend was first put forward:

    this proposal is late to the party, fails to acknowledge those who have been advocating similar approaches for some years, and touts a target for gains in healthy life span that is somewhat less than the actuaries and system biologists think will be attained in the next 10 to 20 years by present trends and research directions.

    ...

    The Longevity Dividend proposal is primarily a political position - which should instantly explain most of its deficiencies to those who follow the way in which funding politics works. It's the first step in a long engagement with large-scale government funding sources (such as the National Institute on Aging) in an attempt to steer future funds into the sorts of moderate programs supported by its authors. That Miller, et al, are doing this at all illustrates, amongst many other things, a concern that future funding will dry up in favor of groups presently moving to advocate healthy life extension - such as those system biologists, or supporters of the Strategies for Engineered Negligible Senescence.

    My prediction for the next decade: the trail to radical life extension, and to increasing public understanding and support for medicines to repair aging, will be blazed by philanthropic and private venture funding.

    Posted by Reason at April 23, 2008 7:35 PM | TrackBack (0)

    Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising and other forms of inappropriate behavior are likely to be deleted.










    Remember personal info?