"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

  
Search

Required Reading
Activism and Advocacy
Calorie Restriction
The Community, Visualized
Cryonics
Envisaging a World Without the FDA
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
The Most Important Debate
Stem Cells, Regenerative Medicine
SENS, Negligible Senescence
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
LifeStar Institute
Methuselah Foundation
Mprize for Longevity Research
Science Against Aging (Translate)
SENS Foundation

On the Causes of Aging
Accumulating AGEs
The Failing Immune System
Junk in the Lysosome
Mitochondrial Free Radicals
Senescent Cells
Other Causes of Aging

Benefiting From Medical Research
How to Read Scientific Research
Researching Therapies and Clinical Trials

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
Being Older for Longer?
What About Retirement?

Recent Entries

  • Subtleties of Calorie Restriction and Evolution
  • Signs of the Times: Engineered Organs in the Popular Press
  • Genescient Envisioned as Sirtris++
  • Help the Immortality Institute Fund Research Into Laser Ablation of Lipofuscin
  • The Singularity's Time in the Sun
  • Deciphering the Machine By Pulling Out Cogs and Flipping Switches
  • Scientific American on Alzheimer's Research
  • The Downward Spiral
  • A Male-Only Longevity Mutation in Mice
  • Cryonics and Economic Incentives
  • Bid in a Charity Auction For a Portrait of Aubrey de Grey
  • You Have To Do Better Than That
  • Failing Memory and the Failing Immune System: Reversible?
  • A New Spanner to Throw Into the Works of Cancer
  • The Benefits of Falling Costs in Biotechnology
  • SENS 4: Early Registration and Abstract Submission Deadline Approaches
  • A Cautionary Tale and a Point of Principle
  • On the 2009 AGE Conference
  • An Update on Decellularization / Recellularization
  • Accumulating Mitochondrial DNA Damage: More Harm or Less Repair?

    Blogs of Interest
    Accelerating Future
    Ageing Research
    Anti-Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Future Current
    FuturePundit
    grailsearch.org
    green light go
    In Search of Enlightenment
    Longevity Science
    Marginal Revolution
    Metamagician and the Hellfire Club
    Metamodern
    Methuselah Foundation Blog
    Mises Economics Blog
    Nanodot
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
    Responsible Nanotechnology
    ScienceBlogs
    Sentient Developments
    Singularity Hub
    Singularity Institute Blog
    The Loom
    The Speculist
    Transumanar

    Archives (Monthly)

    July 2009
    June 2009
    May 2009
    April 2009
    March 2009
    February 2009
    January 2009
    December 2008
    November 2008
    October 2008
    September 2008
    August 2008
    July 2008
    June 2008
    May 2008
    April 2008
    March 2008
    February 2008
    January 2008
    December 2007
    November 2007
    October 2007
    September 2007
    August 2007
    July 2007
    June 2007
    May 2007
    April 2007
    March 2007
    February 2007
    January 2007
    December 2006
    November 2006
    October 2006
    September 2006
    August 2006
    July 2006
    June 2006
    May 2006
    April 2006
    March 2006
    February 2006
    January 2006
    December 2005
    November 2005
    October 2005
    September 2005
    August 2005
    July 2005
    June 2005
    May 2005
    April 2005
    March 2005
    February 2005
    January 2005
    December 2004
    November 2004
    October 2004
    September 2004
    August 2004
    July 2004
    June 2004
    May 2004
    April 2004
    March 2004
    February 2004
    January 2004

    Creative Commons License
    Attribution, noncommercial, no derivative works. Play nice.

  • Monday, November 8, 2004

    How Far To Go With Health Optimization Using Old School Technologies?

    I was intending to title this post "How Far Down the Rabbit Hole?" but decided that was unfair to many of those in the business of optimizing health and healthy life span through presently available technologies. I currently have my hands on a review copy of Fantasic Voyage: Live Long Enough to Live Forever, the book by Ray Kurzweil and Terry Grossman. You may recall that I am unhappy with the strong focus on old school ("Bridge One" in their terminology) technologies, medical knowledge, and health optimization via supplementation.

    I have to throw up my hands at this point. The world has more than enough people who are taking the Life Extension Foundation, A4M and similar paths. We don't need more sellers of vitamin shakes. I think that history demonstrates that when dedicated advocates for healthy life extension research start to focus on old school technologies, their fervor and original message becomes diluted and lost. They change into simple health advocates focused far more on selling largely ineffective present day technologies than supporting medical research goals for the future.

    That shouldn't stop you from stepping out to pick up a copy, however. If you are someone who found a book like Roy Walford's Beyond the 120-Year Diet useful, then you will probably get just as much out of Fantastic Voyage. In it's own way, it's a big step forward for the realm of lifestyle and health advocacy, explicitly taking on and discussing transhumanist ideas associated with extending the healthy human life span. The focus is, however, very much on Bridge One / the old school, with the expectation that staying healthy for another twenty years will bring you amazing further benefits due to new medical science.

    My suspicion has always been that this approach takes future advances in medical technology - and the rate of advancement - too much for granted. I don't think it is a given that we will achieve the goals required for radical life extension soon enough to help those of us alive now. Advances in specific fields of medicine require widespread public support to drive the necessary large-scale funding, whether that funding is private or public. (From the other side of the coin, it's possible that folks like Ray Kurzweil think that I take the implementation of Bridge One/old school technologies for granted - but I look out at the world and see any number of people working hard on that problem, while all too few are looking to the future).

    So how much time should you spend working on optimizing your own health - using what are, frankly, pretty crude tools in the grand scheme of what is possible - versus working to accelerate medical research and bring about healthy life extension more rapidly? This is very personal decision based on a number of factors, and I don't attempt to discuss it at great length at the Longevity Meme. To pick a few:

  • Money

    Do you have enough money to buy supplements and access to medical technology now with an unknown chance that they will work as advertised? Would you be better off saving most of that money for future healthy life extension procedures that may turn out to be pretty expensive?

  • Evaluation

    There is no reliable way (right now, in any case) to evaluate the effects of lifestyle and medical choices aimed at prolonging your healthy life span - short of waiting, that is. What do you consider reasonable evidence for a good chance of effectiveness? How effective per dollar expended does a treatment or lifestyle choice have to appear to be before you would adopt it?

  • Many people obtain great satisfaction from tinkering with supplement regiments and other old school technologies for health. It's much like working on a car - only you don't find out whether you're actually getting that last 10% of extra performance until it's too late to make a difference. I suspect that the lack of cut and dried answers makes it all the more appealing to a certain set of people.

    For my money, as I've said before, I suspect that we can't presently do much better than well thought-out calorie restriction, moderate exercise, a good relationship with your physician, and sensible, moderate supplementation - at a cost of at most a few hundred dollars a month, and probably much less, depending on your definition of "sensible, moderate supplementation." You can work a great deal harder and spend a lot more money, but what will you have to show for it? It's a big point to argue, and many people spend a lot of time and effort doing just that.

    I think we can do better. I say put all that extra effort into supporting medical research for longer, healthier lives. Future technologies to greatly extend your healthy life span won't come about any faster if you are spending your time and money tinkering ever-finer gains out of 20th century supplements and lifestyle options.

    Posted by Reason at November 8, 2004 6:37 PM | TrackBack (0)

    Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising and other forms of inappropriate behavior are likely to be deleted.










    Remember personal info?