News-Medical.net reports on an interesting advance in our understanding of stem cell repair mechanisms: "To regenerate unhealthy tissue, stem cells must first move toward the effected area. It had never been known how stem cells [are] able to home precisely to the site of injury or disease ... Using a simulated stroke model, the collaborators found that the chemokine SDF-1 alpha, secreted by injured or inflamed neural tissue, acts like an SOS signal and summons implanted human neural stem cells to the site of injury ... The stem cells appear to migrate to the site of an injury by engaging in a special kind of movement called 'chain migration' in which the cells slide and guide on top of each other, laying down a path for each other, much like a colony of ants moving from their nest to a source of food."
20
Dec
2004
How Stem Cells Find Damaged Tissue
Comments
Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising, and other forms of inappropriate behavior are likely to be deleted.
First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
- Monthly News and Blog Archives
- Newsletter Archive
- Using the Fight Aging! Content Feeds
- Fight Aging! on the Kindle
Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
Creative Commons
- All of Fight Aging!, with the exception of the introductory articles, is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Creative Commons licensed Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.