A press release at Newswise details an important advance towards controlled differentiation of embryonic stem cells: "The Johns Hopkins Medical Institution laboratory of John Gearhart has taken another small step on the road toward replenishing damaged cardiac tissue with pre-cursor cardiac cells grown from human embryonic stem cells (ES cells). Gearhart and his colleague, Nicolas Christoforou, here reveal preliminary data demonstrating what they say is a highly reproducible system for deriving cardiac progenitor cells from ES cells through controlled differentiation." Scientists are much further down the path of controlling stem cells than even a year ago - and this is the key to developing regenerative therapies capable of fixing age-related damage to our organs and tissues.
06
Dec
2004
Towards Controlled Differentiation
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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