(From Newsweek). "Are the changes in the brain that accompany aging caused by damage to the underlying genes involved in functions such as learning, memory and the transmission of nerve impulses? Exciting new research suggests that they may be, and the findings could eventually help predict and prevent degenerative brain diseases like Alzheimer's and Parkinson's." The spectrum of possible degenerative conditions in the brain is as wide as the brain is complex - the well known conditions are simply those we see most often. Far greater understanding of brain genetics and cellular biochemistry is absolutely necessary for significant extension of the healthy human life span. What lies beyond cured Alzheimer's in a much longer life? We have no idea yet.
09
Jan
2005
Genes And The Aging Brain
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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