Wired reports on efforts to replicate the ability of some animals to regenerate entire organs. "Lop off a newt's leg or tail, and it will grow a new one. The creature's cells can regenerate thanks to built-in time machines that revert cells to early versions of themselves in a process called dedifferentiation. Researchers who study this mechanism hope one day to learn how to induce the same 'cell time travel' in humans. If the cells go back far enough, they become stem cells, which researchers believe hold promise for treating many diseases. ... In newts and some other animals with the ability to regenerate, cells at the site of an injury can revert to their embryonic stem-cell stage and can become another type of cell in that creature's body."
08
Apr
2005
Questing For Dedifferentiation
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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