The BBC provides an overview of recent research into why stem cells fail with age and what can be done about it: "The study found special stem cells come to the rescue of damaged young muscles, but are not triggered in older ones. ... tests on mice suggest something in young blood spurs the stem cells into action to repair the muscle damage. ... We need to consider the possibility that the niche in which stem cells sit is as important in terms of stem cell aging as the cells themselves. ... This is an exciting leap in the research. It proves the fact that you can reverse this problem. But it's no small task to identify the factor in the blood that's involved." It's good to see this work gaining wider notice.
07
May
2005
More On Stem Cell Aging, Young Blood
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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