"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

  
Search

Required Reading
Activism and Advocacy
Calorie Restriction
The Community, Visualized
Cryonics
Envisaging a World Without the FDA
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
The Most Important Debate
Stem Cells, Regenerative Medicine
SENS, Negligible Senescence
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
LifeStar Institute
Methuselah Foundation
Mprize for Longevity Research
Science Against Aging (Translate)
SENS Foundation

On the Causes of Aging
Accumulating AGEs
The Failing Immune System
Junk in the Lysosome
Mitochondrial Free Radicals
Senescent Cells
Other Causes of Aging

Benefiting From Medical Research
How to Read Scientific Research
Researching Therapies and Clinical Trials

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
Being Older for Longer?
What About Retirement?

Recent Entries

  • Subtleties of Calorie Restriction and Evolution
  • Signs of the Times: Engineered Organs in the Popular Press
  • Genescient Envisioned as Sirtris++
  • Help the Immortality Institute Fund Research Into Laser Ablation of Lipofuscin
  • The Singularity's Time in the Sun
  • Deciphering the Machine By Pulling Out Cogs and Flipping Switches
  • Scientific American on Alzheimer's Research
  • The Downward Spiral
  • A Male-Only Longevity Mutation in Mice
  • Cryonics and Economic Incentives
  • Bid in a Charity Auction For a Portrait of Aubrey de Grey
  • You Have To Do Better Than That
  • Failing Memory and the Failing Immune System: Reversible?
  • A New Spanner to Throw Into the Works of Cancer
  • The Benefits of Falling Costs in Biotechnology
  • SENS 4: Early Registration and Abstract Submission Deadline Approaches
  • A Cautionary Tale and a Point of Principle
  • On the 2009 AGE Conference
  • An Update on Decellularization / Recellularization
  • Accumulating Mitochondrial DNA Damage: More Harm or Less Repair?

    Blogs of Interest
    Accelerating Future
    Ageing Research
    Anti-Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Future Current
    FuturePundit
    grailsearch.org
    green light go
    In Search of Enlightenment
    Longevity Science
    Marginal Revolution
    Metamagician and the Hellfire Club
    Metamodern
    Methuselah Foundation Blog
    Mises Economics Blog
    Nanodot
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
    Responsible Nanotechnology
    ScienceBlogs
    Sentient Developments
    Singularity Hub
    Singularity Institute Blog
    The Loom
    The Speculist
    Transumanar

    Archives (Monthly)

    July 2009
    June 2009
    May 2009
    April 2009
    March 2009
    February 2009
    January 2009
    December 2008
    November 2008
    October 2008
    September 2008
    August 2008
    July 2008
    June 2008
    May 2008
    April 2008
    March 2008
    February 2008
    January 2008
    December 2007
    November 2007
    October 2007
    September 2007
    August 2007
    July 2007
    June 2007
    May 2007
    April 2007
    March 2007
    February 2007
    January 2007
    December 2006
    November 2006
    October 2006
    September 2006
    August 2006
    July 2006
    June 2006
    May 2006
    April 2006
    March 2006
    February 2006
    January 2006
    December 2005
    November 2005
    October 2005
    September 2005
    August 2005
    July 2005
    June 2005
    May 2005
    April 2005
    March 2005
    February 2005
    January 2005
    December 2004
    November 2004
    October 2004
    September 2004
    August 2004
    July 2004
    June 2004
    May 2004
    April 2004
    March 2004
    February 2004
    January 2004

    Creative Commons License
    Attribution, noncommercial, no derivative works. Play nice.

  • Wednesday, August 17, 2005

    Kurzweil's Predictions, Complexity Management and the Future of Healthy Life Extension

    Over at the Longevity Meme, I recently pointed to very good commentary on the implications of Ray Kurzweil's predictions for our life spans - how close are we to agelessness attained through advanced technology? With regard to the varied predictions, economist Arnold Kling seems to be on much the same page as I am; his recent piece at Tech Central Station reminded me of arguments I've made in the dim and distant past on the pace of development. He says:

    In comparing the predictions that turned out to be conservative with the predictions that turned out to be optimistic, I detect a clear pattern. Generally speaking, the more open-ended the problem and the more adaptive that the machine needs to be to provide a solution, the less far along we are in arriving at a technological solution. One way to put this is that we can construct tools, but we cannot construct agents.

    In other words, progress towards general (and/or strong) artificial intelligence - a grail for many transhumanists and other futurists - has been slower than we'd like. The level of difficulty has been consistently underestimated in the past, and I see this as one part of a larger underestimation of any form of complexity management. You may recall seeing this idea put forward in a variety of 1990s writing on the topic of nanotechnology; the production of millions of nanorobots wasn't thought to be as hard as the process of controlling and managing those nanorobots in a useful fashion - strategies for information processing are as much the key to future medical technologies as nanoscale and molecular manufacturing. Complexity is hard, both to manage and estimate in advance.

    Now replace "nanorobot" with "human cell" and that's where we are today with biotechnology. Biological systems - such as your body, or even just a small piece of it - are immensely complex. The reason researchers can make meaningful progress today with medical technology such as gene therapies and stem cell research is that they are, effectively, tweaking settings on existing machinery that largely handles the complexity management itself. Our grasp of how things work - based on our ability to process information and build the tools required to gather information and effect change - is now adequate for this task, just as it is almost adequate to guide existing biological machinery to build replacement tissue and organs in a useful, controlled manner. But it seems to me to be a very large leap - in terms of managing complexity - to go from where we are today to reach the point of, for example, replacing biochemically complex systems within the body with artificial substitutes. Or reverse-engineering the brain, that sort of thing.

    People are working on making this future a reality, the technologies of information processing are advancing by leap and bound, and science will get there eventually. The bigger question to my mind - being a first things first sort of person - is whether the first generation and intermediary technologies of healthy life extension, each better than the last, prove to be effective stepping stones. Will early SENS or regenerative medicine therapies enable us to live healthily for long enough to see a Kurzweilesque tomorrow? Or live healthily for long enough to to use the next, nore effective therapy that will take us into Kurzweil territory? Will these working anti-aging medical technologies be developed at all? That is, as I have often said, up to us.

    Posted by Reason at August 17, 2005 7:52 PM | TrackBack (5)

    Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising and other forms of inappropriate behavior are likely to be deleted.










    Remember personal info?