"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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  • Tuesday, October 25, 2005

    $20,000 SENS Challenge Update

    An update to the $20,000 Strategies for Engineered Negligible Senescence (SENS) Challenge can be found at MIT Technology Review editor Jason Pontin's blog:

    Contrary to Mr. Bartlett's story, we have received a number of interesting responses to the challenge - and a group of biologists is, I know, preparing a large, detailed critique of SENS. We still lack a review panel, however, who will review the critiques.

    Good to hear that progress is being made; we all win when the research community comes forth to engage in scientific debate on the points, merits and problems of SENS - as it has largely avoided doing to date. Open, honest debate is how we move forward in the process of gaining support for the development of real, working anti-aging medicine - by putting more minds to work on developing the best possible selection of paths forward and persuading more scientists and funding organizations to get the research done.

    Pontin also makes a helpful clarification to the SENS Challenge rules:

    The full text of any critique can be of any number of words, but any submission should include an abstract of 750 words. In fact, that had always been the spirit of the Challenge ("The form of the submission must be a core document of no more than 750 words, although additional footnotes, citations, and references can be of any length"), but I was perhaps less than clear in my expression.

    A substantiative critique of SENS on merits and points of science is exactly the sort of step forward that this challenge is designed to elicit if it is in fact met. Having researchers discussing SENS on the record allows advocates of directed healthy life extension research the open scientific debate they want. The desired end result is a clear, rapid path to working anti-aging medicine that is supported by a large portion of the scientific community, whether it be SENS, a revised version of SENS, or something completely different.

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    Posted by: Kip Werking at October 25, 2005 7:13 AM

    Fascinating. I can't wait to read these critiques.

    [Posted by: Kip Werking at October 25, 2005 7:13 AM]

    Posted by: g.w. fourmyle at November 15, 2005 6:19 PM

    unlike cetain Sothern Hmisphere conifers, the Cresote Mesqite, or 1 mil-year+ Aspen clones---humans remain clueless as to aging's actual source---rather unlikely we may discover what 'higher' plant-life is aware of---most consider them 'unaware'of anything---notably neither ancient Greeks nor most aboriginal, even European (Asgard) Pagans, Druid, etc.---they respect trees or even 'seeming burning bushes'---

    in fact, many cultures attribute the human form to be 'designed' by plant-life---for symbiotic need, as the 'yucca' and its 'wasp'---it's quite simple---we must have them, whilst they have no apparent, absolute need of us.

    the tradgedy of modern 'science' is that 'one hand never sees the other'. did Maxwell see what was clear to Marconi? does Macy's tell Gimble's?

    if i were looking to extend human life-spans, i would be investigating how these plants do it---but that takes a botanist, not a medical research dr. perhaps they should 'see' one another's utility---become 'generalist'---who seem to have vanished in academia.

    [Posted by: g.w. fourmyle at November 15, 2005 6:19 PM]

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