Tissue engineering of nerves is moving forward nicely, as this News@UofT piece notes: "The design used coil-reinforced hydrogel tubes that promoted nerve regeneration equivalent to that of nerve autografts; a polymeric coil embedded within the wall structure of the nerve guidance channel created a reinforced polymeric channel that significantly enhances regeneration by ensuring that the tube stays open, allowing severed peripheral nerve ends to regenerate both inside and beyond the tube. ... What was innovative about this design was that it used a coil-reinforced hydrogel, a soft material. Nerve is a very soft tissue, and we wanted to match the mechanical properties of soft tissue to the channel we're implanting."
11
Nov
2005
Building New Nerves
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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