"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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The Causes of Aging
Accumulating AGEs
Buildup of Amyloid Between Cells
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Declining Lysosomal Function
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Healthy Life Extension Explained
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Recent Entries

  • The Conservative View of Progress in Applied Cancer Research
  • More on Stem Cell Technology and the Rise of Medical Tourism
  • Resting Metabolic Rate and Aging, Another of Metabolism's Complexities
  • Capabilities in Stem Cell Science Are Advancing Rapidly
  • Incentives and Cryonics
  • Videos From the Foresight 2010 Conference
  • A Steady Flow of New Donors at the Methuselah Foundation
  • Manipulating Fat in the Context of Slowing Aging
  • On Medical Tourism For Stem Cell Therapies
  • Cells, Hearts, and Brains
  • Rapamycin Research Rolls Onward
  • Reversing Blindness in Retinitis Pigmentosa With Stem Cells
  • The Body Does Work to Break Down Damaging Aggregates
  • A Few Cancer Stem Cell Articles
  • The Latest on Mitochondrial Uncoupling
  • Longevity Research at the Science Network
  • Journalists Are In the Business of Gathering Eyeballs, Not Truth
  • @ging, a New Aging Science Blog
  • Redefining Bionics Again
  • Encouraging Transparency in Life Science Fundraising

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    grailsearch.org
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    Fight Aging! is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.

  • Sunday, November 13, 2005

    Maximum Life Foundation

    I was reminded of the Maximum Life Foundation today, the brainchild of David Kekich, who you might recognize from the donor list for the MPrize for anti-aging research and his sponsorship of the Immortality Institute film, Exploring Life Extension. Kekich aims to craft a vehicle, a form of investment fund, to bridge the gap that presently exists between real anti-aging science, commercialization, and venture capital - a gap I touched on in a recent post. From the Maximum Life Foundation website:

    Historically, significant financing for biomedical technologies in the U.S. has come from government-related and other private non-profit sources. Over time, the changing political economy has led to a shortfall of these traditional funding sources . This is especially true for life extension technologies targeted at maximizing longevity while maintaining a high quality of living.

    For a while, private equity venture capital fund managers perceived this trend as an opportunity for venture capital placements. Some prominent successes have been achieved. However, this biomedical sector generally could not keep pace with the high returns obtained in ever decreasing time periods in other non-regulated (or less regulated) technology sectors.

    Most venture funds, for example, have become increasingly impatient to harvest returns from their investments, many expecting an "exit" within only 2-4 years. This trend has been adverse for many biomedical technologies, since they generally have a much longer gestation cycle than communications, electronics or information technologies. In addition, many biomedical technologies require regulatory approvals, which further increases development costs and lengthens the investment cycle.

    This is a real problem for the commercialization of longevity or real anti-aging research today. You either need philanthropic investors with a much longer time horizon and level of commitment to the end goal, or you need novel investment models that garner good enough backing, management and reputation to both lock up money for longer and deliver good returns over that longer time frame. At root, the problem is regulation - something that can only lead to slow progress, high costs and poor results. Here, you see part of the mechanisms that lead to this sorry result; when laws are created to make it hard and expensive to achieve worthwhile goals, then investment funds will pour away into other less regulated fields.

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