01
Feb
2006
Mitochondria Under Calorie Restriction
(From PubMed). The practice of calorie restriction (CR) makes for better, more efficient mitochondria it seems: "Age-related accumulation of cellular damage and death has been linked to oxidative stress. ... Mechanisms responsible for the antiaging effects of CR remain uncertain, but reduction of oxidative stress within mitochondria remains a major focus of research. ... We have focused our research on a related, but different, antiaging mechanism of CR ... mitochondria under CR conditions show less oxygen consumption, reduce membrane potential, and generate less reactive oxygen species than controls, but remarkably they are able to maintain their critical ATP production."
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