"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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The Causes of Aging
Accumulating AGEs
Buildup of Amyloid Between Cells
The Failing Immune System
Declining Lysosomal Function
Mitochondrial DNA Damage
Senescent Cells
Other Causes of Aging

Required Reading
Calorie Restriction
The Community, Visualized
Cryonics
Engineered Negligible Senescence
Envisaging a World Without the FDA
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
The Odds of Human Longevity Mutations
The Need For Activism and Advocacy
Stem Cells, Regenerative Medicine
Twelve Ways to Extend Mouse Life Span
The Vital Debate in Aging Research
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
Campaign Against Aging
Campaign for Aging Research
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Mprize for Longevity Research
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Benefiting From Medical Research
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Objections Answered
Boredom
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Being Older for Longer?
What About Retirement?

Recent Entries

  • The Conservative View of Progress in Applied Cancer Research
  • More on Stem Cell Technology and the Rise of Medical Tourism
  • Resting Metabolic Rate and Aging, Another of Metabolism's Complexities
  • Capabilities in Stem Cell Science Are Advancing Rapidly
  • Incentives and Cryonics
  • Videos From the Foresight 2010 Conference
  • A Steady Flow of New Donors at the Methuselah Foundation
  • Manipulating Fat in the Context of Slowing Aging
  • On Medical Tourism For Stem Cell Therapies
  • Cells, Hearts, and Brains
  • Rapamycin Research Rolls Onward
  • Reversing Blindness in Retinitis Pigmentosa With Stem Cells
  • The Body Does Work to Break Down Damaging Aggregates
  • A Few Cancer Stem Cell Articles
  • The Latest on Mitochondrial Uncoupling
  • Longevity Research at the Science Network
  • Journalists Are In the Business of Gathering Eyeballs, Not Truth
  • @ging, a New Aging Science Blog
  • Redefining Bionics Again
  • Encouraging Transparency in Life Science Fundraising

    Blogs of Interest
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    Alcor News
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    April's CR Diary
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    Distributed Republic
    Ethical Technology Blog
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    Future Current
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    grailsearch.org
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    HumanPlus
    In Search of Enlightenment
    Marginal Revolution
    Maximum Life Foundation Blog
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    Mises Economics Blog
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    Fight Aging! is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.

  • Monday, March 27, 2006

    Pledge to Join the MPrize's Three Hundred at PledgeBank

    I gave a nod of thanks to the first 87 members of The Three Hundred in the latest Longevity Meme Newsletter:

    Eighty-seven people have so far chosen to join The Three Hundred, generous supporters of the Methuselah Foundation and mostly folk of quite modest means. As taxes come and go in the US again, I think it's worth pointing out that The Three Hundred help to keep the foundation within the arcane boundaries of 501(c)3 nonprofit status as the larger donations mount.

    While we all have our varying opinions on taxes and regulation - and I'm sure you know mine by now - I think that any excuse is a good excuse to point out just how much the Three Hundred are contributing to the future of meaningful anti-aging research and healthy life extension advocacy. I strongly suggest that you consider joining: where else can you leverage so much positive change for the future of health and longevity from a couple of dollars a day?

    MPrize supporter Eric Boyd emailed me today with a positive step forward:

    I have been trying to get up my dedication to join The 300, but it's a lot of money. I gave a little last year. In order to motivate/bind myself to join The 300 I have created a pledge:

    http://www.pledgebank.com/Mprize300

    With promotion on your blog I am sure that we can acheive this pledge. Help me cure aging!

    I confess that I have not been following the development of Web 2.0-style philanthropic and nonprofit tools like PledgeBank as closely as I should, but this is an excellent utilization. A pledge of support for the MPrize for anti-aging research is exactly the sort of thing these services can help to enable.

    So, you there in the audience, the folk who have been thinking about stepping up to make a real difference to the future of health and longevity - how about proving Eric right?

    I will become a member of "The 300" at Mprize.org but only if 20 other people will too.

    ...

    The 300 is a group of people supporting an anti-aging prize fund. Each member donates $1000/year to the prize. If 20 people signed up, that would add half a million dollars to the prize over the next 25 years, enough to make the prize significantly more attractive to researchers. Join me and help us cure aging!

    $1,000 per year is a cup of coffee a day - many people of modest means lose more than that to careless finance or candy. These early years, in which advocacy is just as important as science, are a unique opportunity to leverage small amounts of money into world-changing progress. You can invest tens or hundreds of thousands of dollars over a lifetime of work, giving you comparatively good health and medical care in old age - but all that will come to naught if you haven't also invested in ensuring a future that includes working healthy life extension technologies. Suffering, aging and dying with a large 401k is still suffering, aging and dying; wealth cannot buy medical sevices that failed to come into being for lack of support.

    Advocacy by organizations like the Methuselah Foundation and associated groups has had a large effect in just the past few years. You don't have to look back very far to see that a few advocates - with a few dollars, donated by people just like you and I - have engineered a sea change in the way the media and the scientific mainstream view and talk about healthy life extension.

    You can help make this process even faster and more effective: sign Eric's pledge and join The Three Hundred.

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