More Linking: Diabetes and Cancer
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Inflammatory conditions can already be linked to cancer and obesity is linked to inflammation and diabetes. Medical News Today here notes another biochemical linkage: a study "has defined the function of p110 alpha, the flag-ship molecule of the eight member PI3K family, which is one of the most frequently activated pathways in cancer. ... p110 alpha controls the action of insulin and other key hormonal signals that play roles in growth, diabetes and obesity. p110 alpha is frequently mutated or overexpressed in cancer, and the results of the present work imply that cancer cells hijack a key signalling pathway to fuel their energy needs and drive their proliferation and survival. The current work has far-reaching implications, given that several million of people are affected by metabolic disorders, and every year, several hundreds of thousand new cancer cases with mutations in p110 alpha are diagnosed."

Link: http://www.medicalnewstoday.com/medicalnews.php?newsid=41578

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