As noted at wisbusiness, it takes a long time to run a study on calorie restriction (CR) and aging in primates: "A calorie-restriction experiment that began in 1989 with a group of rhesus monkeys under the care of the Wisconsin National Primate Research Center is entering the 'golden years' of the study, and the monkeys are showing no signs of slowing down. ... The monkeys in the oldest group are now about 25, being equivalent to 60-year-old humans ... How well are these calorie-restricted monkeys aging compared to their control group counterparts? They are doing exceedingly well ... showing no obesity, better blood glucose control and, based on studies from the other projects funded by the grant, fewer cellular defects and less muscular atrophy."
14
Apr
2006
Project 2's Rhesus Monkeys
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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