An interesting piece on amyloidosis from the e-journal of the Age Management Medicine Group: "The diseases with which amyloid has been most commonly associated, type 2 diabetes and Alzheimer's disease, are notable for their contribution to decreased quality of life, and mortality, in the elderly. But even among supercentenarians - those living to 110 or more - amyloidosis has emerged as a prime suspect for eventual cause of death. ... What, then, is the connection between amyloidosis and aging? To some extent, this depends upon who you ask - as does the question of whether amyloid buildup can be prevented or reversed. This illustrates the large amount of research being conducted in this area, and constantly emerging knowledge that results."
17
May
2006
Aging and Amyloidosis
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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