The next step in the $20,000 SENS Challenge is now online at the MIT Technology Review. Three critiques of the Strategies for Engineered Negligible Senescence (SENS) - the start of a roadmap to effective therapies to prevent and repair degenerative aging - and biomedical gerontologist Aubrey de Grey's rebuttals are available for consideration by the recently formed panel of judges. Good to see progress towards greater engagement and debate by the scientific community! Science is not advanced when the old guard refuses to debate new ideas and paradigms on the merits - constant, robust examination is a pillar of the scientific method. Only by widening the debate within and surrounding the scientific community can the SENS proposals be made more robust, and formed into the best possible course towards radical life extension within our lifetimes. You'll find more thoughts over at Fight Aging!
08
Jun
2006
SENS Challenge Submissions Unveiled
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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