If you are interested in learning more about the Strategies for Engineered Negligible Senescence (SENS), as well as debating its merits with knowledgeable folk, I recommend a visit to the SENS forum hosted by the Immortality Institute.
Supporters of the SENS proposals and overlapping efforts - such as the LysoSENS research and MPrize for anti-aging research organized by the Methuselah Foundation - have quite different views on the future and emphasis of areas within SENS, not to mention the ethics that come with it. The ethos of full steam ahead to radical life extension is not a big tent position yet (you have to be much more moderate to obtain big tent status in 2006, sad to say), but it's big enough to shelter a number of very interesting debates and challenges. For example:
- Is SENS Complete? Does Achilles heel need binding?
- telomere loss, which part of sens deals with this?
- Improving SENS? Breaking it down... We'll start with chromosomal DNA damage
- Allotopic Expression & the "Mitochondrial Problem" ... & alternative solutions
Jump right on in - it's fascinating stuff, and very accessible to the interested layperson.