The Boston Globe looks at a good example of present day research and development at the tissue engineering side of regenerative medicine. Pervasis Therapeutics is working to "fix arteries and veins not with tools, but by wrapping them in a gelatinous sheath of living, healthy cells. ... a 'cellular Band-aid' - a soft wrapper lined with a healthy colony of living blood-vessel cells. ... surprisingly, he found that they didn't need to be stuffed inside injured blood vessels to help them heal properly. Even wrapped around the outside of the artery, the cells appear to spur healing on the inner surface. In essence, the wrap fixes arteries by rebuilding them inside-out. ... If his idea works in humans, he said, it would show that you don't need to fully rebuild an organ to replace it. ... It could very well be that you could get 95 percent of the functionality that you wish, without getting anywhere close to 100 percent of the structure."
02
Oct
2006
Cell Wraps to Repair Blood Vessels
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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