From Ouroboros, just returned from the 2006 CSHL Meeting on Molecular Genetics of Aging: "The meeting itself was at the same time exciting and grueling: There's so much happening in the field right now; one has the feeling of drinking from a firehose ... With a few days' remove from the experience, however, I keep returning to one theme: This field has exploded in the last dozen years. Without in any way meaning to denigrate the progress in study of aging prior the early 90's, the specific field in question at this conference (molecular genetics of aging) barely existed then. ... Starting in 1993, however, that began to change. ... I want to single out two papers that mark [for me] the beginning of the era of a true molecular genetics of aging. Both have had tremendous impact on the field over the ten years since - at the CSHL meeting, more than half of the talks were in some way based on the founding observations in these two papers."
16
Oct
2006
Perspectives on a Decade of Research
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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