"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

Email Contact
reason -at- fightaging -dot- org

  
Search

The Causes of Aging
Accumulating AGEs
Buildup of Amyloid Between Cells
The Failing Immune System
Declining Lysosomal Function
Mitochondrial DNA Damage
Senescent Cells
Other Causes of Aging

Required Reading
Calorie Restriction
The Community, Visualized
Cryonics
Engineered Negligible Senescence
Envisaging a World Without the FDA
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
The Odds of Human Longevity Mutations
The Need For Activism and Advocacy
Stem Cells, Regenerative Medicine
Twelve Ways to Extend Mouse Life Span
The Vital Debate in Aging Research
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
Campaign Against Aging
Campaign for Aging Research
LifeStar Institute
Immortality Institute
Maximum Life Foundation
Methuselah Foundation
Mprize for Longevity Research
Science Against Aging (Translate)
SENS Foundation

Benefiting From Medical Research
How to Read Scientific Research
Researching Therapies and Clinical Trials

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
Being Older for Longer?
What About Retirement?

Recent Entries

  • The Conservative View of Progress in Applied Cancer Research
  • More on Stem Cell Technology and the Rise of Medical Tourism
  • Resting Metabolic Rate and Aging, Another of Metabolism's Complexities
  • Capabilities in Stem Cell Science Are Advancing Rapidly
  • Incentives and Cryonics
  • Videos From the Foresight 2010 Conference
  • A Steady Flow of New Donors at the Methuselah Foundation
  • Manipulating Fat in the Context of Slowing Aging
  • On Medical Tourism For Stem Cell Therapies
  • Cells, Hearts, and Brains
  • Rapamycin Research Rolls Onward
  • Reversing Blindness in Retinitis Pigmentosa With Stem Cells
  • The Body Does Work to Break Down Damaging Aggregates
  • A Few Cancer Stem Cell Articles
  • The Latest on Mitochondrial Uncoupling
  • Longevity Research at the Science Network
  • Journalists Are In the Business of Gathering Eyeballs, Not Truth
  • @ging, a New Aging Science Blog
  • Redefining Bionics Again
  • Encouraging Transparency in Life Science Fundraising

    Blogs of Interest
    @ging
    Accelerating Future
    Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biology of Aging
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Foresight Institute
    Future Current
    FuturePundit
    grailsearch.org
    green light go
    HumanPlus
    In Search of Enlightenment
    Marginal Revolution
    Maximum Life Foundation Blog
    Metamagician and the Hellfire Club
    Metamodern
    Methuselah Foundation Blog
    Mises Economics Blog
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
    Responsible Nanotechnology
    ScienceBlogs
    Sentient Developments
    Singularity Hub
    Singularity Institute Blog
    Sonia Arrison
    The Speculist
    The Technological Citizen

    Archives (Monthly)

    March 2010
    February 2010
    January 2010
    December 2009
    November 2009
    October 2009
    September 2009
    August 2009
    July 2009
    June 2009
    May 2009
    April 2009
    March 2009
    February 2009
    January 2009
    December 2008
    November 2008
    October 2008
    September 2008
    August 2008
    July 2008
    June 2008
    May 2008
    April 2008
    March 2008
    February 2008
    January 2008
    December 2007
    November 2007
    October 2007
    September 2007
    August 2007
    July 2007
    June 2007
    May 2007
    April 2007
    March 2007
    February 2007
    January 2007
    December 2006
    November 2006
    October 2006
    September 2006
    August 2006
    July 2006
    June 2006
    May 2006
    April 2006
    March 2006
    February 2006
    January 2006
    December 2005
    November 2005
    October 2005
    September 2005
    August 2005
    July 2005
    June 2005
    May 2005
    April 2005
    March 2005
    February 2005
    January 2005
    December 2004
    November 2004
    October 2004
    September 2004
    August 2004
    July 2004
    June 2004
    May 2004
    April 2004
    March 2004
    February 2004
    January 2004

    Creative Commons

    Creative Commons License

    Fight Aging! is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.

  • Thursday, October 12, 2006

    The Memetic Success of Calorie Restriction

    As a recent general interest health article illustrates, the practice and benefits of calorie restriction (CR) are enjoying a newfound spread of understanding in wider culture. It wasn't more than a few years ago that CR was very much on the fringe, known and practiced by only a few. Now, CR is marked by its absence in any common sense article on good health practices.

    Rats fed 30 percent less than normal live 30 percent longer than usual -- and in a recent study at the Washington University School of Medicine in St. Louis, the hearts of the leaner human calorie-cutters appeared 10 to 15 years younger than those of regular eaters. In other research, calorie restrictors improved their blood insulin levels and had fewer signs of damage to their DNA. Eating less food, scientists believe, may reduce tissue wear and tear from excess blood sugar, inflammation, or rogue molecules known as free radicals.

    Edward Calabrese, Ph.D., and Mark Mattson, Ph.D., have opted for "calorie restriction lite."

    Calabrese, a professor of toxicology and environmental health sciences at the University of Massachusetts, Amherst, dumped the midday meal. Mattson, chief of the laboratory of neurosciences at the National Institute on Aging, has done without breakfast for 20 years.

    Try it

    Skip a meal a day. You don't need to try to cut calories; Mattson's research suggests you'll naturally consume less that day. Or try fasting one day a week. Just drink plenty of water.

    Rigor that is not, but the basic ideas are there: less food, maintain the right nutrition, and reap the benefits. The evidence to date suggests that at least some of the benefits scale with the reduction in calories: mild CR brings mild benefits; resistance to age-related disease, and possibly a meaningful extension of maximum human life span.

    The spread of knowledge regarding calorie restriction is nothing short of an impressive success for the healthy life extension community. It shows just what can be done when advocacy and small, active interest groups intersect with the scientific community in a synergy that pushes both sides forward. Funding is hard to find without interest, knowledge and support; it's hard to raise support and educate the world without new science to back you up. But folk have managed to bootstrap calorie restriction research and public knowledge of the practice of calorie restriction into a growing, self-sustaining process.

    Well done.

    The take-away lesson here: this shows that we can do exactly the same - and better - for any aspect of scientific anti-aging research we set our minds to. It's not rocket science, and we have a lot of lives to save - so the faster we get this bus moving, the better!

    Technorati tags: , , ,

    Posted by Reason

     
    Share |

    Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising, and other forms of inappropriate behavior are likely to be deleted.










    Remember personal info?