"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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The Causes of Aging
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Buildup of Amyloid Between Cells
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Recent Entries

  • The Conservative View of Progress in Applied Cancer Research
  • More on Stem Cell Technology and the Rise of Medical Tourism
  • Resting Metabolic Rate and Aging, Another of Metabolism's Complexities
  • Capabilities in Stem Cell Science Are Advancing Rapidly
  • Incentives and Cryonics
  • Videos From the Foresight 2010 Conference
  • A Steady Flow of New Donors at the Methuselah Foundation
  • Manipulating Fat in the Context of Slowing Aging
  • On Medical Tourism For Stem Cell Therapies
  • Cells, Hearts, and Brains
  • Rapamycin Research Rolls Onward
  • Reversing Blindness in Retinitis Pigmentosa With Stem Cells
  • The Body Does Work to Break Down Damaging Aggregates
  • A Few Cancer Stem Cell Articles
  • The Latest on Mitochondrial Uncoupling
  • Longevity Research at the Science Network
  • Journalists Are In the Business of Gathering Eyeballs, Not Truth
  • @ging, a New Aging Science Blog
  • Redefining Bionics Again
  • Encouraging Transparency in Life Science Fundraising

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  • Wednesday, November 22, 2006

    Grouch, Snark, Pessimism and Inertia - All Still Fashionable

    It's pleasant to see that the fine art of the snooty anti-science piece is being kept alive even in this age of research breakthroughs and new knowledge every other week. No sense in moving forward - or advancing your own personal store of knowledge on a topic - when you can pad out a few thousand words with cheap shots and an exhortation upon the limits of what you know. On this theme, I thought I'd point out a couple of articles.

    This first one is a determined defense of avoiding the opportunity to extend an enjoyable, healthy life via calorie restriction (CR). I'll say this for the somewhat snarky NYM piece last month - at least the author got out there, did the research, and tried the practice of CR. You'll have a watch a brief advertisement to read this Salon piece:

    A distorted sense of self-satisfaction, while on the whole a cheerier disorder than outsized self-loathing, can still be troubling, especially when it is the result of having forsaken eating habits that many people would love to be able to enjoy. When Matt Lauer introduced "Today's" CR segment by dramatically asking, "Could food itself be the problem?" it was hard not to wonder how insane we've become to devote airtime (larded with food commercials, no less) to demonizing something that people all over the world do not have enough of. Is it so that people who can afford organic scallops can live to be 150 while everybody else dies their regularly scheduled death?

    As I said, cheap shots, either calculated or ignorant; some people seem to make a fair living by turning out that sort of thing, however. It takes a certain distasteful point of view to stand behind the idea that only the rich are capable of putting in a little effort to plan their diet, and that CR is therefore some hitherto unseen form of class warfare. Equally distasteful: that simple reporting from the world of science has context based on your preferences for socioeconomic organization. But enough of that.

    On the plus side, there are plenty of resources online that people can use to learn about calorie restriction and the research backing it. There really is no such thing as bad publicity in an era of search engines, and the calorie restriction community is a gateway to other communities and initiatives aimed at the development of more effective means to extend healthy life span. If you're interesting in calorie restriction, you should also be interested in the Longevity Dividend project, SENS, the Methuselah Foundation, and so forth.

    The more the merrier, and even dumb articles mean that more folk will come to realize that aging is not set in stone. From that realization will come the support and understanding needed to grow the healthy life extension community and build a larger funding base for serious research aimed at putting a halt to aging.

    The second article I wanted to link to today concerns the state and future of stem cell science, and is a touch more subtle in its attack. You'll always see articles of this nature as the first wave of research and commercialization in a new field fades into the second wave. Most of the early companies fail or dramatically reduce their stated goals - this is very much par for the course in biotechnology and medical research, or indeed any other field. The early investors take a high risk, but the potential rewards are great indeed, so in they dive. Equally par for the course are the solomn analysts come to pronounce on the corpse; most such dirges look pretty silly a decade later.

    In short, yes, stem cells do have the potential to turn into more specialized cells (that is what we mean by a stem cell). But after eight years of trial and error, scientists have not yet shown that they know how to nudge or coax or direct any given cell in a desired direction -- for example, into the dopamine producing cells that are needed to combat Parkinson's disease.

    "It looks hard to me, so we'll never make the progress we'd like!" If I had a dime for every time I've seen some variety of that sentiment ... well, I'd have a fair-sized pile of dimes. Meanwhile, progress continues: tools become cheaper, capability per dollar increases.

    Tune up your nonsense filters; these sorts of things come in cycles, and it looks like it's that time again.

    Technorati tags: ,

    Posted by Reason

     
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    Posted by: T. at November 23, 2006 5:22 AM

    "There really is no such thing as bad publicity in an era of search engines"

    This is nonsense. Search engines can find you anything. Does it imply that everything in the world has a perfect publicity?

    I've noticed that you're always finding a reason to justify you efforts to make you look perfect and blame everything on others (dumb peasants that are scared of any medicine).

    I'll tell you something. I've tried to spam over internet forums with link mprize, sens, and other sites. I even wrote 3 emails to magazines. All have ignored me. When I asked why, they replied, that it was uninteresting to read so they didn't bother.

    But I've talked to several people in person and explained it my way. They were very enthusiastic about it.

    Look. There's not even a slogan under mprize logo on mprize.org site that explains what it is. You have to read small text to find out. Personally it took me to read about 10 different pages and watch dozen of videos to get an idea. Most people don't bother to spend few hundreds of hours to dig through search engines.

    One may think that life, death, health, time are unambiguous terms. But when you talk to people each person has a completely different idea of those things and has a unimaginably weird believes. I want to say that we need one page that explains all this mess in an easy way. I haven't found site like this yet.

    [Posted by: T. at November 23, 2006 5:22 AM]

    Posted by: Reason at November 23, 2006 11:36 AM

    No; it means that it is now easy to find factual and/or information on any topic. Thus any publicity that attracts attention to that topic, be it good, bad or indifferent, will lead to more people researching their way into an opinion that is there own. This is the result of the decentralization of the provision of information.

    If you believe you can improve the matters you are criticizing, then weigh in and volunteer. Provide a better design, move things along. That's the only way progress happens.

    [Posted by: Reason at November 23, 2006 11:36 AM]

    Posted by: April at November 23, 2006 2:48 PM

    Love this post!!!!

    Of course, you knew I would.

    It's always nice to hear from someone sane.

    Keep up the good work, Reason!


    a

    [Posted by: April at November 23, 2006 2:48 PM]

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