Mark Hamalainen is funded by the Methuselah Foundation under the MitoSENS banner, a project to replicate fragile mitochondrial DNA in the cellular nucleus and thus prevent its contribution to aging. Like many of the younger generation of bioscientists, he's open about the desired goal of healthy life extension: "it is good to be alive today, so why not tomorrow? I could write a book on all the things I'd like to do that one lifetime isn't enough for. I can understand how it is culturally advantageous (or at least inevitable) to come up with justifications for aging being ok when there is no prospect of intervention. But to maintain those beliefs when intervention is foreseeable is irrational. Any pro-death argument is vastly out of proportion with the horrible reality of aging: the gradual decay of your body that culminates in the ceasing of your existence."
02
Dec
2006
An Interview With Mark Hamalainen
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
- Monthly News and Blog Archives
- Newsletter Archive
- Using the Fight Aging! Content Feeds
- Fight Aging! on the Kindle
Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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