"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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The Causes of Aging
Accumulating AGEs
Buildup of Amyloid Between Cells
The Failing Immune System
Declining Lysosomal Function
Mitochondrial DNA Damage
Senescent Cells
Other Causes of Aging

Required Reading
Calorie Restriction
The Community, Visualized
Cryonics
Engineered Negligible Senescence
Envisaging a World Without the FDA
Healthy Life Extension Explained
Introductory Articles
Longevity Meme Newsletter
The Odds of Human Longevity Mutations
The Need For Activism and Advocacy
Stem Cells, Regenerative Medicine
Twelve Ways to Extend Mouse Life Span
The Vital Debate in Aging Research
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
Campaign Against Aging
Campaign for Aging Research
LifeStar Institute
Immortality Institute
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Mprize for Longevity Research
Science Against Aging (Translate)
SENS Foundation

Benefiting From Medical Research
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Objections Answered
Boredom
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Being Older for Longer?
What About Retirement?

Recent Entries

  • The Conservative View of Progress in Applied Cancer Research
  • More on Stem Cell Technology and the Rise of Medical Tourism
  • Resting Metabolic Rate and Aging, Another of Metabolism's Complexities
  • Capabilities in Stem Cell Science Are Advancing Rapidly
  • Incentives and Cryonics
  • Videos From the Foresight 2010 Conference
  • A Steady Flow of New Donors at the Methuselah Foundation
  • Manipulating Fat in the Context of Slowing Aging
  • On Medical Tourism For Stem Cell Therapies
  • Cells, Hearts, and Brains
  • Rapamycin Research Rolls Onward
  • Reversing Blindness in Retinitis Pigmentosa With Stem Cells
  • The Body Does Work to Break Down Damaging Aggregates
  • A Few Cancer Stem Cell Articles
  • The Latest on Mitochondrial Uncoupling
  • Longevity Research at the Science Network
  • Journalists Are In the Business of Gathering Eyeballs, Not Truth
  • @ging, a New Aging Science Blog
  • Redefining Bionics Again
  • Encouraging Transparency in Life Science Fundraising

    Blogs of Interest
    @ging
    Accelerating Future
    Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biology of Aging
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Foresight Institute
    Future Current
    FuturePundit
    grailsearch.org
    green light go
    HumanPlus
    In Search of Enlightenment
    Marginal Revolution
    Maximum Life Foundation Blog
    Metamagician and the Hellfire Club
    Metamodern
    Methuselah Foundation Blog
    Mises Economics Blog
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
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    Fight Aging! is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.

  • Saturday, December 16, 2006

    "Won't Work" and the Entrepreneurial Mindset

    Kevin Dewalt has some nice things to say about Dave Gobel, co-founder of the Methuselah Foundation (and the Mprize for anti-aging research). Stroll over to his blog and take a look:

    As we chatted over lunch, David talked about his many past experiences as an entrepreneur and the challenges he faced in starting the Methuselah foundation. How his idea has evolved…how he connected with Aubrey de Grey…the challenges in getting credibility and the victory of Peter Thiel's donation.

    At some point he began talking about his other endeavors and projects to help make our country safer. At one point in the conversation I found myself slipping into the “why it won’t work” mindset during the discussion. Then I caught myself and laughed internally.

    Here I was in the company of someone who was pursuing perhaps the greatest human endeavor in history. Against all odds and critics, David Gobel was trying to defeat age-related diseases and turn back the aging clock for all of us in our lifetime.

    I mean no disrespect to the other great human accomplishments, but does anyone know of another pursuit which measures up to this level of challenge and importance? Wallking on the moon? Discovery of DNA? Theory of Evolution?

    I can’t think of one. Maybe the guy who discovered fire might argue with me.

    In any case, can you imagine how many people have told David Gobel that his outlandish idea “won’t work”?

    No-one commits absolutely to the fulfillment of a vision if there is any significant doubt of success in their mind. Entrepreneurs of all stripes are people deaf and blind to the cries of "won't work!" in their particular space of endeavor - and we all profit greatly from this mindset, where it is directed towards enabling a better future. Progress is only possible when at least some people are willing to risk financial security to attain a vision, and are willing to work themselves to the bone to see that vision accomplished. This is the mindset necessary to sow and nurture the seeds of new organizations, new technologies and new popular movements.

    The Methuselah Foundation is on the way to a future of grand success; raising more than $8 million in cash and pledges in a few years is ticket enough to move from five and six figure donations to seven-figure fundraising and more. It is enough to influence the direction of longevity science, and start to wake the scientific community to action. It is enough to attract worldwide attention from the philanthropic and medical advocacy community. The challenges of growth faced by the Foundation volunteers today are just as tough as those of two years ago, but the potential rewards and results are far greater now. Success attracts further success, provided you keep putting the work in.

    If you do one thing this year to help make the future a better place, make it a donation of time or money to the Methuselah Foundation. Reward the success to date by helping the Foundation achieve even more in the future; your contribution accelerates progress towards reducing the suffering of hundreds of millions, and eliminating the dreadful toll of more than 100,000 lives lost to aging each and every day. Little else any of us can do will have as much impact on the future well-being of humanity.

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