The Other Side of Stem Cell Research
Permalink | View Comments (0) | Post Comment | Posted by Reason

When I talk about stem cell science, it's usually in the context of goals in tissue engineering and regenerative medicine, especially as they apply to repairing the damage of aging. Organ regrowth, scalable production of large numbers of tailored cells, autologous cell therapies, and so forth.

There's a whole other side to stem cell research, however: making it easier and less costly to both understand disease mechanisms and test therapies in the laboratory. If researchers can reliably use therapeutic cloning - or other methods - to produce pluripotent cells from adult cells, then limits placed on the study of disease mechanisms due to scarity of cell samples vanish. This would be a great step forward:

Scientists have taken skin cells from patients with eight different diseases and turned them into stem cells. ... The stem cells were created by taking biopsies from patients with diseases such as Huntington's and muscular dystrophy.

...

By taking skin cells from diseased patients, returning them to their embryonic form before redirecting them to becoming heart cells, a greater understanding of how heart disease develops can be gained ... They can also be used to test drugs - potentially paving the way for more effective treatments.

The technology in this case is induced pluripotency rather than therapeutic cloning, the use of recently discovered genetic switches to reprogram cells into a stem-cell-like state. Diversity of competing methodologies is a good sign for future progress in any field.

Comments
Post a comment; thoughtful, considered opinions are valued. Please note that comments incorporating ad hominem attacks, advertising, and other forms of inappropriate behavior are likely to be deleted.









Remember personal info?






First Steps

The Causes of Aging

Archives and Feeds

Required Reading

Initiatives

Benefiting from Medical Research

Objections Answered

Blogs of Interest

Creative Commons

  • All of Fight Aging!, with the exception of the introductory articles, is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Creative Commons licensed Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.