The first issue of the transhumanist H+ magazine includes piece on radical life extension by Michael Anissimov and an interview with biomedical gerontologist Aubrey de Grey: "The three hardest aspects of SENS (at present - this could of course change!) are: the relocation of mitochondrial DNA to the nucleus to make mutations in the original mitochondrial DNA harmless; the introduction of microbial (or other foreign) enzymes into our cells to destroy molecules that accumulate in them; and the elimination of our cells' ability to prevent the ends of the chromosomes from shortening with each cell division, combined with stem cell therapies to address the side effects that this will cause. Research is proceeding healthily in all these areas, largely funded by the Methuselah Foundation. ... I'm actually not mainly driven by a desire to live a long time ... what drives me is to put myself (with luck) and others (lots and lots of others) in a position to make that choice, rather than having the choice progressively ripped away from me or them by declining health. Whether the choice to live longer is actually made is not the point for me."

Link: http://www.hplusmagazine.com/