An article from headway looks at some of the work presently taking place in the field of regenerative medicine: "Understanding the regeneration of damaged nerves - and eventually controlling where and when it occurs - could have a large impact on the kind of recovery trauma patients achieve. Walking may be the ultimate goal, but for many patients, regaining bladder function or abolishing neuropathic pain is an immediate priority. To this end, [a team] is identifying the genes responsible for regenerating the nerve's long, branch-like body. Their work begins in organisms like Caenorhabditis elegans and Drosophila melanogaster - tiny worms and fruit flies that are hugely valuable to genetics research. Once a gene has been identified in a fruit fly or worm, scientists can search a database to find its vertebrate homologue, and then test it and manipulate it in a mouse or other animal. ... Once we have used genetics to identify genes that control nerve regeneration, we can develop animal models to find drugs that will mimic the genes in the pathway, or up-regulate their expression."
22
Jan
2009
Mission: Regeneration
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
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- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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