Are there comparatively simple, localized tweaks to human biochemistry that could be tested and implemented in a short enough timeframe to benefit the health and longevity of those of us reading this today? Perhaps. This might be one of them: "Oxygen metabolism (the process by which living cells produce energy), leads to the production of highly reactive oxygen species (ROS), which can cause significant neurodegenerative damage in cells that are unable to protect themselves. This is seen most remarkably in aging cells, which experience both an increase in ROS production and a decrease in defense mechanisms, a condition known as oxidative stress. Through their examination of cells in the laboratory, the researchers concluded that potassium channels are targets of ROS, resulting in modification to the cell that causes neuronal dysfunction. The researchers showed that by modifying a single cysteine residue, they could make the potassium channel resistant to oxidation, thereby allowing for normal functioning of the nervous system."
12
May
2009
Upgrading Our Biochemistry
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
- Monthly News and Blog Archives
- Newsletter Archive
- Using the Fight Aging! Content Feeds
- Fight Aging! on the Kindle
Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
Creative Commons
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