"We are on the verge of a revolution in medicine: understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

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The Causes of Aging
Accumulating AGEs
Buildup of Amyloid Between Cells
The Failing Adaptive Immune System
The Failing Innate Immune System
Declining Lysosomal Function
Mitochondrial DNA Damage
Senescent Cells
Other Causes of Aging

Required Reading
Calorie Restriction
The Community, Visualized
Cryonics
Engineered Negligible Senescence
Envisaging a World Without the FDA
Healthy Life Extension Explained
How to Argue for Longevity Science
Introductory Articles
Longevity Meme Newsletter
The Odds of Human Longevity Mutations
The Need For Activism and Advocacy
Stem Cells, Regenerative Medicine
Twelve Ways to Extend Mouse Life Span
The Vital Debate in Aging Research
What is Anti-Aging?

Initiatives
Biogerontology Research Foundation
Campaign Against Aging
Campaign for Aging Research
Immortality Institute
Lifestar Institute
Longevity Consortium
Maximum Life Foundation
Methuselah Foundation
Mprize for Longevity Research
Science Against Aging (Translate)
SENS Foundation

Benefiting From Medical Research
How to Read Scientific Research
Researching Therapies and Clinical Trials

Objections Answered
Boredom
Inequality and Economics
Overpopulation
Stagnation
Being Older for Longer?
What About Retirement?

Recent Entries

  • Why Are There No 400 Year Old Humans?
  • Commonalities in Risk Factors for Age-Related Disease
  • Investigating Metformin's Mechanisms
  • Progress Towards an Implantable, Bioartificial Kidney
  • $20,000 For a Plan to Remove Buildup of the AGE Glucosepane
  • Fundraising Success for a Mitochondrial Uncoupling Project
  • Thyroid Function and Inherited Human Longevity
  • Longevity in the 21st Century, PowerPoint
  • Comparative Longevity in Ants
  • Cryonics, Process, and Preparation
  • "Hazy on the Topic of How Aging Relates to the Diseases of Old Age"
  • Taking a Look at Mitochondrial Repair Research
  • Fundraising for Mitochondrial Uncoupling Research
  • Anoxia Tolerance and Species Longevity
  • Second Meeting of the SENS Los Angeles Chapter on August 27th
  • A Selection of Singularity Summit 2010 Coverage
  • Another Good Sign for Induced Pluripotency
  • The Balancing Act of Longevity Research Advocacy
  • Artificial Intelligence and Engineered Longevity: the Better Tools Viewpoint
  • Escaping the Hand You Were Dealt
  • Blogs of Interest
    @ging
    Accelerating Future
    Ageing Research
    Alcor News
    Al Fin Longevity
    April's CR Diary
    Andart
    Biology of Aging
    Biosingularity
    CRON Diary
    Cryonics Society
    Depressed Metabolism
    Distributed Republic
    Ethical Technology Blog
    Existence is Wonderful
    Foresight Institute
    Future Current
    FuturePundit
    HumanPlus
    In Search of Enlightenment
    Marginal Revolution
    Maria Konovalenko
    Metamagician and the Hellfire Club
    Metamodern
    Methuselah Foundation Blog
    Michael Batin (Translate)
    Mises Economics Blog
    Ouroboros
    Overcoming Bias
    Pimm - Partial immortalization
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    Creative Commons

    Creative Commons License

    Fight Aging! is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.

    Thursday, February 4, 2010

    Six Years of Fight Aging!

    Fight Aging! was inaugurated at the end of January 2004, a dark age of the distant past that we shining folk of this new era barely recall. Tempus fugit. For all this great passage of time, the Fight Aging! mission remains as I have described it in past years. Constancy is still regarded as a virtue in some quarters, I am told.

    A conversation is presently taking place on the topic of healthy life extension, although it may not always look like a conversation in the traditional sense. It wends its way throughout human interactions and publications; articles, magazines, websites, blogs, actual physical conversations, letters public and private. It is a single pathway in the great marketplace of ideas and culture.

    Sometimes our conversation is hard to find, however. ... someone has to be talking on topic to keep the conversation growing, to avoid lapses in which newcomers might miss the party - hence the existence of Fight Aging!

    Somewhere along the way, I started to use Fight Aging! as a part of my own efforts to better educate myself on the biochemistry of aging, the state of modern biotechnology, and work taking place on longevity science. If the earlier posts contained more advocacy than science, the last couple of years have been fairly evenly divided between those two topics. But the archives have grown large indeed - somewhere in the vicinity of 1800 posts - and almost every topic related to engineered longevity that I consider useful or interesting has been touched on in some way. Indeed, six years of writing has generated more than enough material to surprise me on a regular basis by what turns up in the Fight Aging! archives. Memory is the first thing to go, or so they say.

    So is all this effort getting us anywhere? That is an interesting question, and one that is a challenge to answer. My visibility into the reach of Fight Aging! is limited to what I hear and the statistics on traffic I gather, neither of which are particularly reliable in and of themselves. From what I know, however, I am reasonably certain that readership has remained constant over the past couple of years. On the one hand, talking in detail about fairly complex scientific research is an excellent way to drive people away. On the other hand it seems as though there should be an increasing level of interest in engineered longevity - even if only from those folk who are looking for age-slowing pills and drugs as a result of increased publicity for the search for calorie restriction mimetics.

    My analysis is that Fight Aging! has ossified a little as a pillar (one of many modest pillars) of a forward-looking longevity science community that is not growing very fast. I'm starting to lean towards the present Methuselah Foundation view that working to greatly expand the community of supporters is presently as important as fundraising initiatives.

    Posted by Reason

    Share |
       

    Posted by: David Gobel at February 5, 2010 11:07 AM

    The main thing I have appreciated about Fight Aging has been its (your) unwavering focus and integrity. You have avoided any hint of bias beyond the simple proposition that extending healthy lifespan is an unalloyed good. I would also like to remind you that Fight Aging had a significant part in motivating an anonymous high net worth donor give a million dollars to the Mprize fund (are you out there? thank you again from the bottom of our collective hearts!).

    Also, just for the record, Methuselah Foundation's recent founding investment in Organovo (3d tissue printer) has generated a metric ton of very positive PR for our mission. Just Google news the term Organovo and feast your eyes on the deep and wide reverberations of this new tech/company.

    So, I think all readers of Fight Aging owe you a "WELL DONE"!!!

    Dave

    [Posted by: David Gobel at February 5, 2010 11:07 AM]

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