From Mike Kope, SENS Foundation CEO: "Last night, Peter Thiel hosted 'Breakthrough Philanthropy', a dinner and presentation event showcasing eight non-profit organizations focused upon game-changing approaches to their fields. It was a wonderful opportunity for us to convey our message to a large group of entrepreneurs and philanthropists interested in the genuinely transformative. Our thanks to the Thiel Foundation, and the Seasteading Institute, for their efforts in creating that event. Here are my remarks from the presentation. ... We've gotten very good at conquering infectious diseases. None of you will suffer from polio, or smallpox, or, likely, measles or diptheria. But the truth is, we haven't extended that kind of success to the problems of aging. You will know someone suffering from cancer, from Alzheimer's, from Parkinson's disease. We haven't yet eradicated a single, major age-related disease. This is despite great advances in therapeutics, despite trillions in research underway around the globe, and despite the brightest minds working in an entire, thirty year long biotech revolution. Ten years ago, our CSO Aubrey de Grey first suggested … a slightly different revolution. His core idea was a damage repair model called SENS, and a recognition of a simple problem: when medical science focuses upon disease - when we wait for disease to develop - then what we learn is how to chase the pathology - and we haven't gotten very good at that. But if we look instead at the damage building up as a result of the normal metabolism of being alive, then we can learn to repair that damage before those deadly pathologies develop. That's it; that's all that SENS means: it's a model that steps away from the expensive and tangled 'pathology chase' and focuses instead upon identifying, addressing and removing the damage that is building up inside you; the damage that will eventually cause disease."
First Steps
- Read an Introduction to Living Longer
- Read the Fight Aging! FAQ
- Help Researchers Extend Healthy Life
- Sign up for the Fight Aging! Newsletter
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
- Monthly News and Blog Archives
- Newsletter Archive
- Using the Fight Aging! Content Feeds
- Fight Aging! on the Kindle
Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Enthusiasm for the Slow Road
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- SENS: Engineered Negligible Senescence
- Stem Cells, Regenerative Medicine
- The Three Types of Aging Research
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- What is Anti-Aging?
- Why Prioritize SENS Research?
Creative Commons
- All of Fight Aging!, with the exception of the introductory articles, is published under the Creative Commons Attribution 3.0 license. In short, this means that you are encouraged to republish and rewrite Creative Commons licensed Fight Aging! content in any way you see fit, the only requirements being that you (a) link to the original, (b) attribute the author, and (c) attribute Fight Aging!.
I think you're doing a great job and every year past people will wake up for this idea that is possible to defeat aging.