Improving Control of Stem Cells
A common theme at the Longevity Meme is the scientific path towards ever greater, more precise and useful control over our cells - and stem cells in particular, given their importance to cancer, some manifestations of aging and regenerative medicine. Here, EurekAlert! looks at another step forward: "researchers genetically mapped a stem cell gene and its protein product, Laxetin ... This particular gene is important because it helps regulate the number of adult stem cells in the body, particularly in bone marrow. ... The only stem cell population that has been examined for effects of Latexin to date is in bone marrow. ... it is possible, even probable, that other stem cell populations in tissues such as the liver, skin, pancreas or brain may be similarly affected by Latexin. This could open up new therapeutic strategies such as using stem cells for the treatment of other diseases and conditions such as liver disease, diabetes and central nervous system damage as a result of trauma or stroke. ... The findings also will help scientists develop effective methods to modulate stem cell numbers and function for therapeutic uses, and also provide a better understanding of the age-related changes that occur in stem cells."
Link: http://www.eurekalert.org/pub_releases/2007-01/uok-rft011207.php