SENS3 Posts From Attila Chordash
Molecular biologist Attila Chordash continues to turn out posts on his favored presentations at the recent SENS3 conference on rejuvenation and longevity science. The view of researcher Michael Rose's approach to engineering longevity is interesting: "The script is: breed mice with delayed reproduction over multiple generations (let evolution by natural selection give us the answer of how to build a long-lived animal), and then reverse engineer this answer to develop anti-aging therapies for genetically unaltered humans. The experimental basis of this proposal: Rose's own ancient experiments with fruit flies [showed] that there is a plateau in mortality rates after many generations of breeded Drosophilas with delayed reproduction time which leads to the cessation of the aging process." This is an extension of the search for longevity genes; let evolutionary pressure do some of the legwork first, in terms of identifying the biochemistry that is most important. Still, fundamentally this is a reengineering approach, not a repair approach - and therefore most likely much harder.