Mapping the Role of Foxn1 in Thymic Function

Researchers have of late been mapping the activities and relationships of Forkhead box protein N1 (Foxn1) in the thymus, and the paper I’ll point out today outlines some of the most recent findings. Sadly it isn’t open access, but I’m sure that won’t stop the determined reader in this day and age. This work is of interest to our community of longevity science supporters because increased levels of Foxn1 have been shown to restore a more youthful level of thymic activity in older animals and human cell lines, and have been used to regrow thymic tissue when used in conjunction with cell therapies. Why is thymic activity important? To simplify greatly, the thymus is where new T cells of the adaptive immune system mature after … Continue reading Mapping the Role of Foxn1 in Thymic Function