Randall Parker uses recent research into the genetics of the aging brain as the starting point for some common sense talk on health, aging and the future of anti-aging medicine: "Probably in 20 or 30 years time we will be able to grow replacements for all the internal organs. ... But the brain is our identity and needs to be repaired, not replaced. ... This makes brain rejuvenation much harder than rejuvenation of the rest of the body. We need to slow brain aging because effective rejuvenation therapies for the brain are going to take longer to develop than rejuvenation therapies for the rest of the body. ... Even if you are very confident that a cure for aging will be found before you die that is not a reason to be complacent about your diet and lifestyle. ... Best to delay the onset of assorted maladies as long as you can."
02
Jan
2006
Brain Aging, Common Sense
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
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