Better biotechnology improves the quality of the old-school drug pipeline, as illustrated by this BBC article on a Alzheimer's drug: "Tests in mice have shown the drug, PBT2, prevents build up of the amyloid protein linked to the disease. Protein levels dropped by 60% within 24 hours of a single dose, and memory performance improved within five days. ... Human tests are due to start next month, followed by a major international trial next year. ... This data is compelling and very exciting because it shows that PBT2 not only may facilitate the clearance of [amyloid-beta] from the brain or prevent its production, but more importantly may improve cognition. ... Scientists still have a lot of work to do before a drug could be available for patients. Much more research is needed even to see whether preventing the amyloid build-up is really a true benefit for patients."
26
Jul
2006
A Better Alzheimer's Drug
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
Archives and Feeds
- Monthly News and Blog Archives
- Newsletter Archive
- Using the Fight Aging! Content Feeds
- Fight Aging! on the Kindle
Required Reading
- Calorie Restriction
- The Community, Visualized
- Cryonics
- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
- Introductory Articles
- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
- Stem Cells, Regenerative Medicine
- Twelve Ways to Extend Mouse Life Span
- Transhumanism and Human Longevity
- The Vital Debate in Aging Research
- What is Anti-Aging?
Creative Commons
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