A slice of calorie restriction (CR) life in this article from New York Magazine; more than a little journalistic hyperbole and arrogance tops the feast (as we all know, the boundaries of the world lie at the limits of a journalist's preconceptions, and playing it straight doesn't sell papers), but the author gets the science mostly right: "Seat belts, vaccines, clean tap water, and other modern miracles have dramatically boosted average life expectancies, to be sure - reducing annually the percentage of people who die before reaching the maximum life span - but CR alone demonstrably raises the maximum itself. In lab studies going back to the thirties, mice on severely limited diets have consistently lived as much as 50 percent longer than the oldest of their well-fed peers - the rodent equivalent of a human life stretched past the age of 160. And it isn't just a mouse thing: Yeast cells, spiders, vinegar worms, rhesus monkeys - by now a veritable menagerie of species has been shown to benefit from CR's life-extending effects."
23
Oct
2006
New York on Calorie Restriction
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First Steps
The Causes of Aging
- Accumulating AGEs
- Buildup of Amyloid Between Cells
- The Failing Adaptive Immune System
- The Failing Innate Immune System
- Declining Lysosomal Function
- Mitochondrial DNA Damage
- Nuclear DNA Damage
- Buildup of Senescent Cells
- Other Causes of Aging
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- Engineered Negligible Senescence
- Envisaging a World Without the FDA
- How to Argue for Longevity Science
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- The Odds of Human Longevity Mutations
- The Need For Activism and Advocacy
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- Twelve Ways to Extend Mouse Life Span
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- The Vital Debate in Aging Research
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