More on Longevity Gene Research

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Here's a report on increasingly sophisticated analysis of genes that contribute to natural longevity: "People who live to 100 or more are known to have just as many - and sometimes even more - harmful gene variants compared with younger people. Now, scientists [have] discovered the secret behind this paradox: favorable 'longevity' genes that protect very old people from the bad genes' harmful effects. The novel method used by the researchers could lead to new drugs to protect against age-related diseases. ... researchers were able to construct a network of gene interactions that contributes to the understanding of longevity. In particular, they found that the favorable variant of the gene CETP acts to buffer the harmful effects of the disease-causing gene Lp(a). ... researchers are greatly expanding their longevity research: From the 66 genetic markers examined in this study, they are now using a high-throughput technology that allows them to assay one million genetic markers throughout the human genome. The goal is to find additional genetic networks that are involved in the process of aging."

Link: http://www.aecom.yu.edu/home/news/PRdetails.asp?isPR=1&id=372