If your priority for charitable giving is to reduce human suffering in the world, then by far the most cost-effective approach is to support scientific programs that enable the development of rejuvenation therapies. In comparison to the vast and inflated cost of medicine, the scientific research that produces the means to make new medicines is cheap. Given the right infrastructure of research, advocacy, and networking between the scientific community and industry, new scientific results achieved at low cost, supported by philanthropy, can inspire a great deal of venture capital and other for-profit investment in further development. The following 501(c)(3) charitable foundations are an important part of that growing infrastructure: please support their ongoing efforts to enable human rejuvenation in our lifetimes.
Donate to the LRI Research Center at Lifespan.io
The LRI Research Center at Lifespan.io was formerly the scientific arm of the SENS Research Foundation. Following the merger with Lifespan.io, it continues as the research group and laboratory that led to a number of spin-out companies focused on aspects of rejuvenation via repair of the cell and tissue damage that causes aging, such as Cyclarity. A number of interesting programs remain underway, and are worthy of support.
https://www.lifespan.io/how-you-can-help/
Donate to the Longevity Escape Velocity Foundation
Aubrey de Grey's new Longevity Escape Velocity (LEV) Foundation undertakes similar work in research and advocacy as the SENS Research Foundation, with an initial focus on combining approaches to demonstrate that repairing different forms of cell and tissue damage simultaneously will produce greater, synergistic gains, as expected from a damage-focused view of aging.
Donate to the Methuselah Foundation
The Methuselah Foundation was the original home for the research programs that grew to became the SENS Research Foundation. The Methuselah Foundation continues to perform a range of important work in the field of rejuvenation research, in combination with an allied venture fund, the Methuselah Fund. The primary focus is tissue engineering and production of replacement organs, but they are also involved in numerous other projects relevant to research into aging and rejuvenation.
https://www.mfoundation.org/join-us
Last updated: December 15th 2025