It looks like a drug used to treat diabetes has been found to mimic the healthy life extension effects of calorie restriction in mice. (Reported in Canada Newswire). This is interesting, if early, research that parallels other efforts to discover a way to gain the benefits of calorie restriction without the calorie restriction. As ever, take this with a grain of salt until other researchers validate and build on the findings. Still, I'm happy to see more of this promising line of research. There should be more results coming in the next year or so from ongoing research on the mechanisms of calorie restriction.