This article from Science News Online is a comprehensive and very informative look at the current state of hormone replacement therapy (HRT). HRT is heavily pushed by some sectors of the supplement and medical industy -- they sense money to be made, of course. However, if is unclear as to whether HRT is going to do any given individual more harm than good. The volume and coherence of scientific studies that would make me feel comfortable are simply not there. As always my advice is to be a late adopter; wait for science to study and come to definitive conclusions before trying anything that will affect your health. Listen to your physician, and research, research, research. It's your life and health, after all!