The New Haven Register prints an easy-reading article on some of current attempts to unravel the genetic underpinnings of calorie restriction and aging. Calorie restriction is a demonstrated, effective means of extending healthy lifespan. Understanding the genetic effects associated with calorie restriction offers the hope of therapies that radically extend healthy lifespan without any associated diet and lifestyle changes. Biomarker Pharmaceuticals is a venture-funded company currently attempting to capitalize on this sort of research. Its existence is a sure sign that the larger medical research market is taking this very seriously.