"Labs around the world are crawling with prodigiously long-lived flies, worms, and mice." Starting from that comment, SAGE Crossroads proceeds to debunk the idea that increased longevity requires a trade-off in some other aspect of life or health. While there are always dissenters, it doesn't look like the naysayers have a very compelling case in this instance. Research to date does indeed present a good case that - through advances in medical science - we could have it all: radically increased healthy life span with no significant downside. Of course, this is dependant on funding and public support, which is why we need activism and education.