This CBN article gives an overview of research on resveratrol, a compound thought to activate genes in a similar way to calorie restriction. You may recall the spate of inaccurate articles on resveratrol in 2003 when the mainstream press learned the compound is found in red wine. This piece is more responsible, but - like most articles on supplements - is uninformed with regard to the potential of near future medicine to extend the healthy human life span. Supplement researchers are generally aiming low, at extending the healthy human lifespan by a few decades. This is an admirable goal in and of itself, but supplements can only take you so far. To beat the conditions of aging (and aging itself), better medical technologies will be needed.