Betterhumans notes that Pfizer is already developing a drug to mimic the effects of a known longevity gene on high density lipoprotein (HDL, or "good" cholesterol). You may recall news items from last year on that topic. Of course it remains to be seen as to whether this new drug has the desired effect on longevity and resistance to heart disease. Still, it's a sign that greater understanding and new technology across the research spectrum is leading to better drug development. It is becoming easier with each passing year to identify beneficial effects and more rapidly find drug candidates that will cause those effects. We are - slowly - moving out of the era of pulling levers in the dark, and into an era of acting on knowledge.