CORDIS reports on a new integrated European science project aimed at bringing regenerative medicine (based on adult stem cells) for bones, cartilage, and ligaments from basic research all the way to clinical applications. "Over 50 million European citizens suffer from some form of connective tissue disorder. Age-related degenerative disorders (such as osteoporosis, osteoarthritis) are among the diseases with the highest socio-economic impact, requiring hospitalisation, rehabilitation and home care." Projects like this demonstrate that real progress has been made in stem cell basics. The scientific and business communities see a clear path forward, and are starting to move more rapidly.