From ScienceDaily: "Imagine that by altering the function of a single gene, you could live longer, be thinner and have lower cholesterol and fat levels in your blood. Medical College of Georgia researchers are using a tiny worm called C. elegans to transform that vision into reality." This article looks at work on the "I'm not dead yet" (Indy) gene and its role on longevity. This is yet another gene that appears to have similar effects to calorie restriction: changes in metabolism, improved health and extended healthy life span. It's usually a long way from worms to people in the world of medicine, but the Indy gene does exist in humans. This is promising work in a field that is attracting a fair amount of attention these days.