The International Herald Tribune has published a good article on calorie restriction, a diet demonstrated to extend life span in mammals and at the very least produce impressive health benefits in humans. "Scientists, who are still uncovering exactly how the process works, believe the effects of caloric restriction are an evolutionary response to allow creatures to survive during adversity and live long enough to reproduce when conditions improve. Guarente recently reported that caloric restriction triggers a release of stored fat, which may tell the body 'it's time to hunker down for survival.' In addition, he suggests that caloric restriction may spur the body to become more efficient at using nutrients." We should be seeing more results from the CALERIE study next year - hopefully as good as the first set.