Alzheimer's and Stem Cell Research

Since today is World Alzheimer's Day, it seems appropriate to take a look at what people are saying about stem cell research and Alzheimer's disease. Chris Mooney has been keeping track, and has a number of posts on the topic:

It's a favorite talking point of the anti-embryonic stem cell research crowd: ES cell transplants will never cure Alzheimer's, they claim. Is it true?


Lessons that can be learned from stem cell transplants for Parkinson's and other types of neurodegenerative disease will reveal a great deal about cell signaling and cell environment that could be applied in Alzheimer's.


Stem cell transplant therapy doesn't sound like a good bet for Alzheimer's, as scientists fully admit. However, basic research using embryonic stem cells, including from cloned embryos, holds considerable promise for increasing our understanding of the development of the disease, and that in turn could lead to potential cures. So, it's not at all disingenous to talk about Alzheimer's in connection with stem cell research, unless you misleadingly claim that stem cell transplant therapies are going to cure Alzheimer's.

Modern bioinformatics ensures that serious research into any disease tends to improve our overall knowledge of human biochemistry and cellular processes.


Stem cells which can be derived from both umbilical cords and vrious parts a persons' body (apart from aborted fetuses) may be able to be used when stimulated by nerve growth factor to regenerate dying neurons in alzheimers; my question is: could stem cells involved in cancer proliferation possibly be used to destroy amyloid beta protein or even genetically mutated cells involved inn molecualr ligand binding.

Posted by: Jacob Mack at February 2nd, 2005 11:03 AM

Salicylates can be harmful to the liver and have a long list of contraindictations which can damage the smooth endoplasmic reticulum of the liver. Maybe (depending on extent of damage) milk thistle along with proper diet and exercise would benefit such people. Or perhaps other mild anti inflammatories (which also reduce the risk of alzheimers could be used).There are naturally occuring supplements which do this.

Posted by: Jacob Mack at February 2nd, 2005 11:08 AM

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